Although excessive amounts of certain vitamins and minerals have been shown to have negative effects, biotin is not. “Currently there is no upper limit for biotin intake, due to the lack of reports of adverse events with high intake,” Cording explains.
More precisely, "no adverse effects were observed with very high doses or oral intake, up to 200 mg daily (which is 20,000 micrograms), so there is no mandatory data to support the effects of direct toxicity," Ferreira added.
A common misconception is that biotin supplements, or increased intake of biotin in general, can lead to breakouts.
Although it was not kept during the study. Hadley King, MD, a board-certified dermatologist, told MBG that it is theoretical that biotin supplements can contribute to skin blemishes by interfering with the absorption of pantothenic acid (vitamin B5). “However, no studies have shown that taking biotin supplements or pantothenic acid deficiency causes [breakouts]The king said.
In addition, the ferries noted: "This is not very easy, because caution should be exercised in high-dose biotin due to the possibility of lab testing interventions for key biomarkers."
In the case of very good things, "vitamin D levels measured by serum 25-hydroxyvitamin D, troponin for cardiac function, HCG for pregnancy tests, biotin megadosing for accurate evaluation of key labs, including thyroid panel results, and others may prove challenging." For this reason, "there is nothing more at the base of biotin, at least not at this extreme, high levels such as 5 mg (5,000 micrograms) and above," Ferreira concludes.
Again, consult your healthcare practitioner for your own unique needs. As Ferreira explains, "Of course there are certain clinical situations under the supervision of a doctor where intentionally, high-dose biotin methods are used, but that's not what we're talking about here for the average person."